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The Kinin System (Handbook of Immunopharmacology)
 
 
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The Kinin System (Handbook of Immunopharmacology) (Hardcover)

by Stephen G. Farmer (Author) "The existence of the Kallikrein-kinin system was first disclosed nearly 50 years ago when a series of coincidental discoveries by two independent groups came together..." (more)
Key Phrases: kallikrein gene expression, tissue kallikrein activity, kinin receptor agonists, New York, Agents Actions, Natl Acad (more...)
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Editorial Reviews

Product Description
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities.
From the prepublication reviews:
"A delicious masterpiece."
--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases.

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* Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.
* Provides a distinctly immunopharmacological approach to the kinin system.
* Reviews of the role of kinins in disease and inlcudes data from human studies.
* Includes information that is fully up-to-date and comprehensive.

From the Back Cover
A comprehensive, timely book covering all aspects of the kinin system, from its discovery to the pathophysiology, pharmacology and molecular biology of the mechanisms regulating kinin production and kinin receptors in health and disease, Several chapters contain new information on the gene expression, regulation and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the roles for kinins in pain, angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinitis, myocardial ischemia and other diseases.

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